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Juvederm Facial Filler - Mesa, Arizona.

If you are unhappy with changes in your facial appearance due to aging, injectable fillers like Juvederm can help. If you have hollows under your eyes, sunken cheeks, thin lips, or deep facial folds, then Juvederm can correct them to give you a smoother, younger-looking face. Juvederm is derived from a compound found naturally in your skin that diminishes with age, and its rejuvenating effects can last for up to a year.

Juvederm is one of many cosmetic fillers we offer at East Valley Ophthalmology. Which one is right for you depends on your skin and your cosmetic goals. To get personalized recommendations, please call 480-981-6111 or contact us today to schedule your consultation.

Juvederm - Obagi NuDerm Special $500 per syringe and receive Obagi NuDerm products at 25% off, limited to available Obagi stock. East Valley Ophthalmology discount or special offers are available for a limited time only, may not be combined with any other offer, and may be revised or discontinued at any time without notice. Other restrictions may apply. Please call our office for details. 480-981-6111.


Dr. Nirenberg of East Valley Ophthalmology is highly experienced in performing treatments throughout the face with Juvederm. He knows how to get great results and when another filler might be a better option.


Juvederm injectable gel adds volume and smoothness to your face by gently filling in facial wrinkles and folds like your “smile lines” or “parentheses” (the creases that run from the bottom of your nose to the corners of your mouth). Juvederm comes in two formulations — Juvederm Ultra and Juvederm Ultra Plus.

Where Juvéderm Can Be Used

Juvederm is a very flexible injectable filler that can be used in most places where additional volume is desired. This includes:

  • Lip augmentation
  • Hollows under the eyes
  • Sunken cheeks
  • Nasolabial folds (parenthesis lines around the mouth)

Because of its smoothness, some people prefer the results of Juvederm in lip augmentation and treatment wherever the skin is very thin. Although Juvederm can last for up to a year, the length of results depends on the area being treated, with lips lasting the shortest and under eye hollows the longest.

Immediate Results!

With Juvederm, the injection process takes only about 15 minutes and results are immediate. Plus, there's minimal recovery or downtime. So you can step into our office for treatment and step right back into your life.

Frequently Asked Questions about Juvederm

What is Juvederm?

Juvederm injectable gels are non-animal based, colorless hyaluranic acid gels that are injected into the facial tissue to smoothe wrinkles and folds, especially around the nose and mouth.


What makes Juvederm different from other dermal fillers?

Juvederm is the ONLY hyaluronic acid dermal filler FDA approved to last up to one year. The unique process that goes into manufacturing Juvederm provides a high concentration of cross-linked hyaluronic acid for long-lasting results. It also works to create a gel of smooth consistency that flows easily into the skin and provides a completely natural look and feel. All other hyaluronic acid dermal fillers currently on the market are made of granular consistency gels. And, Juvederm is the first hyaluronic acid dermal filler that has demonstrated its safety and effectiveness in persons of color.

What is hyaluronic acid?

Hyaluronic acid is a naturally occurring substance normally found in the skin, muscles, and tendons of all mammals, including the human body. Its purpose is to deliver nutrients, hydrate the skin by holding in water, and act as a cushioning agent. In addition to its use as an aesthetic treatment, hyaluronic acid has also been used for more than 20 years for injection into arthritic joints to aid movement as well as for eye surgeries and wound repair.

What is cross-linked hyaluronic acid?

“Uncross-linked” hyaluronic acid in its natural form is in a liquid state. “Cross-linking” is the process through which hyaluronic acid is made into a gel product that can be injected into the skin for long-lasting results.


How is Juvederm different from Botox Cosmetic?

Juvederm injectable gel is a “next-generation” hyaluronic acid dermal filler that provides volume and is used to treat wrinkles and folds resulting from a loss of volume beneath the surface of the skin, such as perioral lines and nasolabial folds (lines around your mouth and nose). Juvederm restores your skin's volume for a smooth, natural look and feel.

Botox Cosmetic is not a dermal filler. Botox Cosmetic relaxes muscle activity and is used to treat moderate to severe lines caused by the dominant frown muscles between the eyebrows (the glabellar area). This allows the two vertical lines between the brows, often referred to as the “11,” to temporarily diminish for a smoother appearance.

How does Juvederm work?

Dr. Nirenberg gently eases Juvederm injectable gel into the mid to deep dermis (below the outer layer of skin) using a fine needle. The Juvederm fills in moderate to severe facial wrinkles and folds such as “smile lines” or “parentheses” (nasolabial folds) and “marionette lines” (oral commissures). Juvederm temporarily adds volume and smoothness to facial tissue and thereby restores a more youthful appearance to the face. Most patients need just one treatment to achieve optimal wrinkle smoothing. Optimal results are achieved when the treatment area is readily distensible and correction can be visualized by manual manipulation (stretching) of the skin. Results typically last six months to one year.

Juvederm works well for cosmetic and plastic surgery applications because hyaluronic acid can absorb up to 1000 times its own weight in water, thereby adding new volume under the surface of sagging skin. Older faces take on more youthful aspects because hyaluronic acid is known to bind with collagen -- the material that supports human facial skin -- and elastin to move more basic nutrients into the skin. Moreover, Juvederm continues working as time goes on by adding even more collagen to the face.

Why does Juvederm come in two formulations?

Juvederm comes in two formulations, Juvederm Ultra and Juvederm Ultra Plus, to allow Dr. Nirenberg to tailor treatment to your unique needs.

  • Juvederm Ultra provides versatility in contouring and volumizing facial wrinkles and folds.
  • Juvederm Ultra Plus is a more robust formulation for volumizing and correcting deeper folds and wrinkles

Can people with different skin colors be treated with Juvederm?

Yes. In fact, Juvederm injectable gel is the first FDA-approved hyaluronic acid dermal filler that has proven its safety and effectiveness in persons of color. Studies with Juvederm showed no increased risk of hyperpigmentation or hypertrophic scarring in patients of color.

How long does a Juvederm treatment usually take?

The injection process takes only about 15 minutes. You'll also need to allow time to consult with Dr. Nirenberg prior to treatment. Prior to wrinkle treatment with Juvederm injectable gel, your complete medical history will be reviewed and you will be informed of the details of the Juvederm treatment process, benefits, results, and potential side effects.

Are Juvederm injections painful?

Injections may cause some discomfort during and after the injection. The amount of pain you experience would depend on your individual tolerance. However, the smooth consistency gel of Juvederm allows Dr. Nirenberg to administer it easily and smoothly using a fine needle. To further minimize discomfort, Dr. Nirenberg may choose to numb the treatment area with either a topical or local injectable anesthetic.

What precautions should I take following my Juvederm procedure?

Dr. Nirenberg will explain in detail what precautions to take following your Juvederm treatment, including when you may resume use of cosmetics. In general, as with any injection site, patients may have mild to moderate reactions that will typically resolve within a few days. For best possible results, you should avoid strenuous exercise, extensive sun or heat exposure, and all alcoholic beverages for 24 hours. Exposure to any of these may cause temporary redness, swelling and/or itching at the injection sites. The application of an ice pack will bring relief.

Does the Juvederm correction last forever?

No. Correction is temporary; therefore, you should be aware that supplemental “touch up” treatments may be required to achieve and maintain optimal results. However, Juvederm is the ONLY hyaluronic acid filler FDA approved to last up to one year, which makes it the longest lasting dermal filler now available.

What are the possible side effects of Juvederm injectable gel?

Most side effects are mild or moderate in nature, and their duration is short lasting (usually less than a week). The most common side effects include, but are not limited to, temporary injections site reactions such as redness, pain/tenderness, firmness, swelling, lumps/bumps, bruising, itching, and discoloration. As with all skin injection procedures there is a risk of infection.

Safety Profile:

  • Frequency and severity of treatment site responses were similar to control treatment sites during extensive clinic studies.
  • The smooth, uniform consistency of Juvederm allows it to flow easily and consistently into the skin.
  • Studies with Juvederm showed no increased risk of hyperpigmentation or hypertrophic scarring in patients of color.

Who should NOT receive Juvederm injectable gel?

Dr. Nirenberg will ask about your medical history to determine if you are a candidate for Juvederm treatment. Juvederm should NOT be used in patients who have:

  • Severe allergies marked by a history of anaphylaxis or a history of or presence of multiple server allergies
  • Patient with a history of allergies to Gram-positive bacterial proteins.

What else should I know about Juvederm?

The following are important considerations for you to discuss with Dr. Nirenberg in order to achieve your best possible results. It is vital that you inform Dr. Nirenberg if any of these might apply to you:
  • If you are using substances that are known to prolong bleeding or bruising at the injection site, such as aspirin or ibuprofin, discontinue at least one week prior to your treatment with Juvederm.
  • If you are considering laser treatment of your skin, chemical peeling, or any procedure that is based on an active dermal response, as there is a possible risk of an inflammatory reaction at the treatment site.
  • If you are on any kind of immunosuppressive therapy or therapy used to decrease your body's immune respons, as there may be an increased risk of infection.
  • If you are pregnant, planning on becoming pregnant, or breastfeeding, as safety for these conditions has not been established.
  • If you are under 18 years of age, as safety for this age group has not been established.
  • If you have a history of excessive scarring (hypertorphic scarring and Keloid formations) and/or pigmentation disorders, as safety for these conditions has not been established.

Although Juvederm has also been used as a lip augmentation agent, to fill in hollow places and scars on the face, the safety and effectiveness of Juvederm for the treatment of areas other than facila wrinkles and folds (such as lips) have not been established in controlled clinical studies.

What did clinical studies on Juvederm show?

Juvederm was the subject of the largest United States clinical study ever conducted on hyaluronic acid dermal fillers.

  • Subjects were followed for 24 weeks after injection.
  • Juvederm injectable gel was injected in one nasolabial fold and Zyplast (a bovine-based injectable dermal filler made from collagen) in the other.
  • Injection sites responses were similar for Juvederm and Zyplast, usually mild or moderate in severity, lasting only a day or so.
  • Juvederm was found to provide a more persistant wrinkle correction than Zyplast within the 24-week study.
  • The percentage of subjects who maintained improvement within the study was 88% with Juvderm compared to 36% with Zyplast.
  • 78%-88% of patients preferred Juvederm injectable gel at six months post-treatment.
  • Patients overwhelmingly preferred Juvderm products over study control.

If you would like further information, please call our office at:


East Valley Ophthalmology

Eye Doctors - Mesa, Arizona

The Best Possible Skin Care

At East Valley Ophthalmology, Dr. Nirenberg performs plastic surgery and anti-aging skin care treatments, as well as taking the time necessary to provide each patient the personal education needed to fully understand their condition, care and options, and to get the best possible outcomes for his patients. Please take a moment to Request an Appointment.


East Valley Ophthalmology
5620 East Broadway Road
Mesa, Arizona 85206

Tel: +1-480-981-6111
FAX: +1-480-985-2426

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